Bremelanotide, also known as PT-141, belongs to a newer class of drugs called melanocortins, which work on the brain neurotransmitter dopamine, increasing sexual desire. Bremelanotide activates the hypothalamic and limbic emotional structures in the brain, which naturally flare during sexual arousal. Specifically, Bremelanotide works at the pre-optic nucleus, which is essential for blood flow to the penis and vulva. The mechanism of action of Bremelanotide involves helping to activate internal pathways in the brain involved in the body’s normal sexual responses. Bremelanotide has been studied in more than 30 clinical trials with over 2,500 people with positive outcomes for both men and women.