Hydroquinone with Tretinoin Combination Cream
Available only by prescription, Hydroquinone Skin Bleaching Cream is a highly potent Rx
bleaching solution that gradually lightens and inhibits hyperpigmentation by altering the
natural processes that cause cell damage. Specifically created to help even skin tone by slowing
melanin production, it dramatically reduces the appearance of dark spots, chloasma, melasma,
freckles and sun damage for an even skin tone. While the hydroquinone helps eliminate dark
spots and even skin tone, the Retinoic Acid or Tretinoin component of this product breaks up
and sheds dead skin cells to reveal fresh new skin underneath.
Important Safety Information for Hydroquinone
People with prior history of sensitivity or allergic reaction to this product or any of its ingredients should
not use it. The safety of topical hydroquinone use during pregnancy or in children (12 years and under)
has not been established.
Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes,
nose, mouth, or lips with water and contact physician.
Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure
sustains melanocytic activity.
Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic
symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall
prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity
is seen more frequently in asthmatic than in nonasthmatic people.
PRECAUTIONS (ALSO SEE WARNINGS):
Treatment should be limited to relatively small areas of the body at one time since some patients
experience a transient skin reddening and a mild burning sensation, which does not preclude treatment.
Pregnancy Category C: Animal reproduction studies have not been conducted with topical
hydroquinone. It is also not known whether hydroquinone can cause fetal harm when used topically on a
pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical
hydroquinone is absorbed systemically. Topical hydroquinone should be used on pregnant women only
when clearly indicated.
Nursing Mothers: It is not known whether topical hydroquinone is absorbed or excreted in human milk.
Caution is advised when topical hydroquinone is used by a nursing mother.
Pediatric Usage: Safety and effectiveness in children below the age of 12 years have not been established.
Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.