... ...

Click here to find out more about these treatments!

Penile Injection Therapy.

Penile Injection Therapy is the most effective medicine for ED.

by Dr. Brent Agin, MD

Founder and CEO


Start my Visit Watch How it Works Video

Penile injections began being administered in 1983 and have proven to be the most effective non-surgical treatment for erectile dysfunction according to the American Urologic Association. For some reason, doctors are not educated on the use of penile injections and so many patients do not even know they exist. As more doctors are learning and becoming more comfortable prescribing penile injections, they are becoming increasingly more popular as a solution to E.D. due to their efficacy and minimal side effects. 

  Administered as a penile self-injection (you administer the injection to yourself), they are considered the most powerful class of anti-erectile dysfunction agents. While the components, on their own, are indicated for a vast number of different conditions, the practice of bringing them together to treat erectile dysfunction has become commonplace in sexual medicine. They are now considered to be the go-to treatment if conventional PDE5 inhibitors (phosphodiesterase type 5), such as Cialis or Viagra are contraindicated, non-responsive or non-tolerated. Once injected, the blend of medications will cause the erectile tissue in the penis to relax, expand and fill with blood, causing an erection within several minutes. The injection is done using a very small needle, inserted into the proper area along the shaft of the penis, so the drug mixture is delivered into the corpus cavernosum.

Penile injections can provide longer and fuller erections allowing you to maintain and improve your sexual health!  Penile injections, unlike most oral medications, can trigger an automatic erection in less than 5 minutes.

The primary reason to choose penile injection therapy over other therapies is that there are minimal undesirable side effects unlike those of FDA-approved oral and other medications.  While the side effects of penile injections are very rare, they can happen, but we tell you how to deal with an erection that lasts more than 3 hours.

Penile injection therapy generally produces reliable, predictable and consistent results and it’s inexpensive – each vial contains 500 units, and a dose is between 5–20 units in most circumstances so you can get up to 25-100 uses out of a single vial of medication.

It takes a commitment to inject at first, but it is almost painless and well worth a few seconds of discomfort for the wonderful results you will achieve. It may take a few times to determine the dosage that is right for you but do not inject more than once per day and no more than every other day. You should learn to inject on opposite sides each time.

  • Avoids the undesirable side effects of oral medications
  • Your erections will be strong and reliable
  • It works consistently
  • Helps eliminate performance anxiety
  • Works in 5-10 minutes and lasts 1-3 hours
  • Allows you to focus on the other aspects of sex

Penile injections began being administered in 1983 and have proven to be the most effective non-surgical treatment for erectile dysfunction (ED) according to the American Urologic Association. For some reason, doctors are not educated on the use of penile injections and so many patients do not even know they exist. Doctors are finally becoming more comfortable prescribing these increasingly popular ED injections due to their efficacy and minimal side effects. 

Administered as a penile self-injection (you administer the injection to yourself), they are considered the most powerful class of anti-erectile dysfunction agents. While the components, on their own, are indicated for a vast number of different conditions, the practice of bringing them together to treat erectile dysfunction has become commonplace in sexual medicine. They are now considered to be the go-to treatment if conventional PDE5 inhibitors (phosphodiesterase type 5), such as Cialis or Viagra are contraindicated, non-responsive or non-tolerated. Once injected, the blend of medications will cause the erectile tissue in the penis to relax, expand and fill with blood, causing an erection within several minutes.

Penile injections can provide longer and fuller erections allowing you to maintain and improve your sexual health!  Penile injections, unlike most oral medications, can trigger an automatic erection in less than 5 minutes.

The injection is done using a very small needle, inserted into the proper area along the shaft of the penis, so the drug mixture is delivered into the corpus cavernosum. The mixture of drugs causes the corpus cavernosum to relax, dilate and become filled with blood, producing an erection. 

We have multiple videos to educate you on how to mix, how to inject the medication painlessly, and what to do if your erection does not begin to subside after 3 hours. We share our knowledge with you on how to properly use this therapy so you can have more enjoyable sexual experiences. [Click here to go to videos]

Why do I have ED?

There is nothing light and humorous about ED – it’s a medical issue affecting many men. There is no need to be ashamed. Erectile dysfunction is, under most circumstances, a treatable medical condition.

A man’s ability to obtain and maintain a satisfactory erection declines due to various factors, such as:
  • Age
  • Psychological factors (including performance anxiety and loss of interest in sex)
  • Obesity
  • Diabetes
  • High blood pressure
  • Smoking
Our goal is to help you have a satisfactory erection so you can focus on sex.

What are the undesirable side effects of FDA-approved oral medications?

The undesirable side effects of FDA-approved oral medications include:

  • Stuffy head
  • Congestion – hard to breathe through your nose
  • Headache
  • Seeing blue lines
  • Lower back pain
  • Sex planning (by having to take oral medications 60 minutes in advance – with possibility of wasted doses)
  • Meal planning (oral medications work best when taken on an empty stomach)
  • You should not consume alcohol while taking oral medications
  • Possible interaction with certain other medications such as nitrates

What is included with the Penile Injections?

We supply 31 gauge diabetic size syringes like children with diabetes use – very tiny needle, your medication, mixing solution, and alcohol wipes. We also include the injectable antidote with your first order at no charge to give you additional comfort and security.

How Do I begin my therapy?

Remember to start low and go slow. It may take a few attempts to find your right dosage and medication.

How do I purchase the oral antidote now to keep on hand?

You will receive the antidote, Phenylephrine, with your initial order. You can continue to refill this with your medication or you can purchase Sudafed 30mg over the counter at your local pharmacy. You must purchase it at the pharmacy counter, not in the aisle.

Go to the pharmacy counter and ask for it by name. The pharmacist may suggest a long-acting option — say no and stick with the Sudafed® 30mg pseudoephedrine pills.  It’s less than $10. You will have to provide your driver’s license. Keep it on hand just in case you may, in the rare event, need to use it as an antidote. Who are not candidates for Penile Injection Therapy?

Do not use penile injection therapy if you have: hypersensitivity or allergy to any component of these formulations (Papaverine HCL, Phentolamine Mesylate, Prostaglandin E1, or Atropine Sulfate); conditions predisposing you to priapism (painful erection lasting 4 hours or more); sickle cell anemia, multiple myeloma or leukemia; anatomical deformation of the penis or penile implants; direction by your physician that sexual activity is inadvisable or contraindicated, or severe cardiac disease.

What if my erection does not begin to go down after 3 hours (or if I want it to go down sooner)?

Remember to start low and go slow. It may take a few different attempts to find your right dosage. This is a very rare side effect that usually occurs from injecting too much medication. Even though it is very rare for patients to experience an erection that does not begin to go down after 3 hours, it is important for you to be fully educated of your options.

Option 1: Take Sudafed (Pseudoephedrine 30mg, Purchased At The Pharmacy Counter)


If you experience the rare event of an erection lasting more than 3 hours, you may take 4 Sudafed (pseudoephedrine) 30mg (purchased at the pharmacy counter, no prescription needed) by mouth once and apply an ice pack between your legs at 20 minute intervals.  If your erection does not begin to go away within the next hour then your will need to inject the included antidote of Phenylephrine HCl Injection. 

Option 2: Inject Phenylephrine HCl (Included In Your Initial Order)

In the extremely rare occurrence that your erection has not started to go down after ejaculation or an hour after taking 4 Sudafed (pseudoephedrine) tablets and applying the ice pack between your legs for 20 minutes, then you will need to administer the injectable penile antidote, Phenylephrine HCl (included in your first order). This antidote is already pre-mixed.

Inject the Phenylephrine HCl directly into your penis just like you injected the original medication (although now your penis will be fully erect). You can review the injection process video at any time (click here to view the instructional video). It will be easier to see the veins that you need to avoid in an erect penis.

Inject 25 units of Phenylephrine HCl 0.1% into your penis. This can be injected at either side of the penis. After injection, the injection site should be compressed and lightly massaged to facilitate drug distribution.  If your erection does not begin to go down after 5 minutes, inject another 25 units. Repeat this process up to a maximum total of 4 injections of 25 units in 5 minute intervals​. Do not exceed 100 units. ​

Again, this is a very rare side effect that usually occurs from injecting too much medication. If your erection still does not start to go down within 1 hour after the injection of Phenylephrine HCl, then take pictures of all your medications and go to the emergency room.


Recommended Therapies

Bi-Mix Injection
INJECTION
SEXUAL HEALTH

Tri-Mix Injection
INJECTION
SEXUAL HEALTH

Quad-Mix Injection
INJECTION
SEXUAL HEALTH

Sildenafil ODT 125mg
INJECTION
SEXUAL HEALTH

Tadalafil ODT 25mg
ORAL
SEXUAL HEALTH

Oxytocin 200IU ODT
ORAL
SEXUAL HEALTH HORMONE

Super Quad-Mix Injection
INJECTION
SEXUAL HEALTH

Melanotan II 10mg
INJECTION
PEPTIDE SEXUAL HEALTH

Bremelanotide (PT 141) Injection
INJECTION
PEPTIDE SEXUAL HEALTH

Phenylephrine HCI (Rescue Vial)
INJECTION
SEXUAL HEALTH

Are you ready to start your online visit today?

Still have questions? Chat with one of our Wellness Advisors now or call (877) 659-6050 to get started today!

Start Online Visit

Still have questions? – Let’s talk before you even spend a penny!

If you are still not sure TelewellnessMD® is the right solution for you, talk to one of our medical support specialists that can explain how our service works and answer any questions you may have on available therapies. We want you to feel completely comfortable before you join our wellness community. Simply fill out the form below to receive a call from medical support specialist.